Cymbalta (Duloxetine) – What It Is and When It’s Used

Cymbalta, whose generic name is duloxetine, belongs to a group of drugs called serotonin‑norepinephrine reuptake inhibitors (SNRIs). It’s prescribed for major depressive disorder, generalized anxiety disorder, fibromyalgia, and certain types of chronic pain. If you’ve been told to start Cymbalta, it means your doctor wants to boost mood chemicals and reduce pain signals at the same time.

How to Take Cymbalta – Dosage Basics

Most adults start with 30 mg once a day, usually taken in the morning. After a week or two, the dose may be increased to 60 mg once daily, which is the common maintenance level. Some people need 90 mg a day, split into two doses, especially for pain conditions. Always swallow the tablet whole with water; don’t crush or chew it. If you miss a dose, take it as soon as you remember unless it’s almost time for the next one—then just skip the missed one.

Common Side Effects and What to Watch For

Typical side effects include nausea, dry mouth, headache, and a bit of fatigue. These usually fade after a few days. A few people notice dizziness when they stand up quickly—so getting up slowly can help. If you develop a rash, swelling, or trouble breathing, stop the medicine and call a doctor right away; those could be signs of a serious allergic reaction.

Another important point is that Cymbalta can affect blood pressure. Your doctor may check it before you start and during follow‑up visits. If you already have high blood pressure, let your provider know; sometimes the dose needs adjusting.

Because Cymbalta changes brain chemistry, it’s crucial not to stop it abruptly. Cutting it off can cause withdrawal symptoms like dizziness, flu‑like feelings, or mood swings. If you need to quit, your doctor will taper you down over a few weeks.

Alcohol can increase the risk of liver problems and make side effects worse, so it’s best to limit drinking while you’re on Cymbalta. Also, tell any new doctor or pharmacist that you’re taking it, especially before surgery, because it can interact with certain anesthesia drugs.

Pregnant or nursing women should discuss risks with their doctor. While some studies suggest a relatively low risk, the decision should be made together with a healthcare professional.

Overall, Cymbalta works well for many people dealing with depression, anxiety, or chronic pain, but it does need a bit of monitoring. Keep a simple log of how you feel, any side effects, and share it with your doctor at each visit. That way you can fine‑tune the dose and stay on track with your wellness goals.